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Sanctuary, the first broadcast caliber Sci-Fi series developed specifically for the Internet and the first to be filmed entirely on Green Screen, stars Amanda Tapping as Dr. Helen Magnus, one of the first female doctors in the Royal College during Victorian England. Dr. Magnus takes over her fathers' sanctuary for supernatural creatures, collected from all over the world. In her work with these creatures, Dr. Magnus has received age longevity. She is joined by her daughter Ashley, played by Emilie Ullerup, and young psychiatric resident Dr. Will Zimmerman, played by Robin Dunne, who may have what it takes to become her new protégé.
In 2008, Sanctuary was picked up by the SciFi Channel and rebooted the series in 60 minute form with the pilot "Sanctuary for All." On November 12, 2008, Sanctuary was renewed for a 13 episode second season.

Kate Freelander resurfaces with a warning about a Hollow Earth plot against an above-ground target, and evidence suggests that Bigfoot may be involved in the attack.

Henry, Declan and a team from the UK Sanctuary go to the Bering Sea to investigate a mystery on a shipwrecked icebreaker, where the crew has killed the Abnormals on board and each other

Two flying Abnormals land on the Sanctuary seeking Magnus' help; Will is temporarily blinded during a riot in Monrovia.

The team tracks an Abnormal fugitive, and discovers that Tesla is the head of a secret research lab for a Homeland Security agency that conducts tests on Abnormals

A hostage situation unfolds when Magnus flies to a remote island off of Africa to meet the Sanctuary's new financial adviser; a shipping container mix up has Will and Henry tracking a missing Abnormal

Magnus must explain a mission that went awry to a UN official as the Sanctuary faces scrutiny following the barely averted Abnormal uprising; Henry's girlfriend turns up with an unforeseen problem

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In the Season 4 premiere, Magnus goes to 1898 London to try to prevent Adam Worth from saving his daughter, an event which would alter the current time line.

Abnormals from Hollow Earth emerge in large numbers from a cave in South Dakota, prompting Magnus to cooperate with the military; and Druitt resurfaces and warns Magnus of a plot he hatched with Adam Worth.

Magnus and Will awake in a strange and terrifying world: The Suburbs.

Strange disappearances in France bring Magnus face to face with her past.

An adventure set in WWII has Magnus joining up with the French Resistance on the eve of D-Day to stop the Nazis from using a device that controls the weather.

Magnus and Tesla probe a Praxian stronghold and uncover secrets about the vampire race. Meanwhile, Kate shares a dark part of her past while tracking a drug operation that uses live amphibious Abnormals.

Will and Henry's double date goes awry when they do a delivery of an Abnormal on the way to dinner.

Will develops scales on his face, and his rapid transformation into a new creature has Magnus reaching out to Hollow Earth for answers.

A dinner date goes awry for Will and Abby when they are abducted at gunpoint on their way to a restaurant. Magnus puts a halt to the team's rescue operation upon determining the identity of their abductors, leaving Will ...

Magnus returns to a disheveled Sanctuary just hours before it is to be inspected by the chief of a UN security team. She first encounters a battered Henry, who claims he was attacked by Will, and learns that Bigfoot is m...

For trespassing in Praxis, the team is sentenced to death, but Ranna needs Magnus to gain insights into Adam and the tremors that are affecting the city. Elsewhere, Druitt contends with cannibalistic creatures.

Seeking a gateway to the secret subterranean city, Magnus leads a treacherous mission to Tibet - telling a bitter Adam that he must stay behind while promising to bring back a cure for their radiation sickness. Because o...

Adam is released from his restraints so that he can help Will find an access point for the hidden city; Magnus and Druitt go to London to find a critical artifact, leaving Will to manage the Sanctuary.

Magnus tells Will about her past with Adam Worth (Ian Tracey) and his link to "The Five"; Tesla divulges that Druitt may have additional information about Adam; Will makes a shocking find while analyzing blood tests.

Her distant past leaves Magnus fighting for her life in an old, abandoned building. And, in order to ensure the safety of Hollow Earth, she must make a deal with the devil – a devil who appears to have come back from t...

Will and Henry travel to the UK to follow up on a werewolf sighting and end up uncovering a dark connection to Henry's past and future.

Kate gains super-hero-like abilities when an Abnormal attaches itself to her for safe keeping.

The team gets a cryptic distress call that could only come from one person...Nikola Tesla.

Magnus and the team go to a bank to retrieve an Abnormal that was stashed in a safe deposit box, which not only hatched prematurely but also escaped, prompting Kate to enforce a less-than-subtle quarantine of the bank's ...

Will suffers from amnesia after his near-death experience; visitors are intent on finding out what is in his memory.

Conclusion. Two ships are wrecked and a tidal wave races toward the coast of Mumbai, India, following Wexford's attempt to kill "Big Bertha." When Wexford tries to kill the creature again, Magnus risks her life to interv...

Magnus, Will and Kate journey to Mumbai, India, to probe a murder that may be linked to the Cult of Kali, whose devotees can allegedly predict disasters, but Will succumbs to a mysterious illness in the course of the inv...

Magnus, Will and Kate travel to Mumbai, India, on their mission to investigation the link to a murder. To make matters worse Will becomes ill before he mysteriously disappears

The team rescues the occupants of a sinking ship off the coast of South Africa and teleport them to the Sanctuary. However, Magnus suspects Druitt of murdering one of the passengers during the rescue.

Magnus and Will investigate a number of inexplicable teenage disappearances. The common denominator in the case seems to be that they all recently spent time at an exclusive rehab clinic in Mexico.

Paying a ...

Magnus is reunited with an old friend, Jimmy who is transporting a valuable elemental Abnormal to the Sanctuary for safety.

But an underground mob accustomed to cashing in on the Abnormal black market, track...

Magnus and Will try to retrieve a sea creature from the coast of Louisiana, but the Abnormal breaks lose in mid-flight, resulting in a crash landing that imperils the duo

Will goes up against the heads of the Sanctuary Network to defend Magnus who is charged with a shocking murder. But as the evidence stacks up against her, even Will has trouble finding a way to convincingly defend her in...

Henry tries to determine why a seemingly docile domesticated abnormal suddenly turned violent after it attacks a research scientist.

A confused Dr. Magnus finds the Sanctuary and surrounding city has been destroyed, but she has no idea how it happened. While searching the remains she is pounced on by a vicious creature, leading to two armed men rescui...

Magnus traps a superhero (Christopher Gauthier) whose lack of finesse affects the team's work. Elsewhere, the discovery of an eggshell remnant puts Will and Declan (Robert Lawrenson) on the hunt for a creature that's loo...

With chaos all around them, the team must come to terms with how to rebuild after the Cabal’s attacks. Magnus takes a methodical approach to prove Ashley is still alive, while Will and Henry take on the daunting t...

Furious at being duped into a trap, Magnus (AMANDA TAPPING) takes on Kate (AGAM DARSHI), demanding information and complete access to her Cabal contacts. The Cabal’s true agenda is revealed and Magnus realizes tha...

The search for Ashley puts Magnus and her allies in the path of Kate Freelander (Agam Darshi), a con artist with ties to the Cabal who divulges the location of a secret facility

Ashley and Henry are captured by the Cabal after breaking into their weapons factory. While being restrained Ashley learns from Dana Whitcomb that the plan they have for the virus to be released worldwide will still go a...

Magnus and her team have to face the possibility of international biological warfare when a virus infects the abnormals, causing them to attack humans. John Druitt makes an unwelcome return to the Sanctuary as, he too, s...

Desperate to get their first exclusive news story Amy Saunders and her cameraman Zach Spencer get inside an evacuated building. Earlier that day three people had been found inside, brutally murdered by a strange creature...

When Danny, and old friend of Will goes missing, his wife contacts him asking for help. With the aid of Helen and Ashley, Will starts searching and they find themselves in an abandoned factory. There is no sign of people...

Magnus and Will investigate a distressing call for help deep below the Bermuda Triangle resulting in a deadly battle to save Magnus's life.

A young artist with an uncanny ability to draw remarkably detailed pictures from memory may be the key to solving a case surrounding the suspicious death of his abusive father.

When Magnus encounters an old acquaintance in Rome, he tells her that the Cabal is planning to seek revenge on her for the events of "Fata Morgana". But she soon learns that his loyalty is not as intact as it was in thei...

When two seemingly harmless abnormals arrive at the Sanctuary, the team finds themselves feeling some unusual animal attraction for one another (TV.com).

A plane crash in the Himalaya Mountains gets more horrifying when survivors are attacked one at a time.

While investigating a series of strange robberies, the Sanctuary team encounters a group of thieves, who seem to possess a strange ability which apparently allows them to literally slip between the cracks of the law..

Dr. Helen Magnus, her daughter Ashley, and the newest member to the Sanctuary, Dr. Zimmerman, travel to Northern Scotland to discover three women in an ancient crypt and bring them back to the Sanctuary for refuge and st...

As Will attempts to help Alexi coup with his abnormality, Helen gets a visitor from her past.

The enigmatic Dr. Helen Magnus recruits insightful forensic psychiatrist Will Zimmerman to join her in the quest to track, study and protect the strange and often terrifying creatures that secretly populate our world.